唤醒中风和未知发作的中风后的生存率 - - 来自挪威中风登记处的全国性观察研究
Mary-Helen Søyland1,2, Arnstein Tveiten1, Agnethe Eltoft2,3
1Department of Neurology, Hospital of Southern Norway, Kristiansand, Norway.
European stroke journal
|January 30, 2026
概括
在所有发病类型中,缺血性中风后的短期生存率在所有发病类型中都相似. 然而,未知发作的中风与已知发作的中风相比,与更糟糕的长期生存有关.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 脑卒中是导致死亡的主要原因,基于中风发病类型的生存数据有限.
- 之前的研究强调,在一般人群中,中风后死亡风险增加.
- 对于唤醒中风和未知发作的中风缺乏具体的生存数据.
研究的目的:
- 为了研究和比较缺血性中风后的短期和长期生存率.
- 分析通过中风发病模式分层的生存数据:已知发病,醒来和未知发病.
- 确定中风发病类型是否影响中风后死亡风险.
主要方法:
- 利用挪威中风登记处 (2014-2023) 的数据,对有史以来首次发生的缺血性中风病例进行分析.
- 短期生存率定义为30天生存率;30天生存者中分析的长期生存率.
- 采用卡普兰-梅尔生存分析和多变量回归来根据发病类型评估死亡风险.
主要成果:
- 包括68,025名患者:45,084名已知发病,12,429名醒来,10,512名未知发病.
- 30天的生存率是相似的:91.3% (已知),92.4% (醒来),91.7% (未知).
- 30天生存者中的5年生存率:65.4% (已知),67.6% (醒来),60.4% (未知). 不知发病的中风显示出较高的调整后死亡风险比率 (1.19).
结论:
- 缺血性中风后的短期存活率是一致的,无论发病方式如何.
- 不知发病的中风与显著较差的长期存活率有关.
- 脑卒中发作的分类对于了解长期预后和死亡风险至关重要.
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