美国成年人口腔健康与代谢功能障碍相关的脂肪性肝病 (MASLD) 之间的关联
Chukwuemeka E Ogbu1, Abhishek Goel1, Anjali Gupta2
1Department of Internal Medicine, Cape Fear Valley Health, Fayetteville, NC, USA.
Clinical and translational gastroenterology
|January 30, 2026
概括
未满足的牙需求和牙与代谢功能障碍相关的脂肪性肝病 (MASLD) 有关. 这些口腔健康问题可能表明MASLD风险更高,特别是在女性中.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 牙科医学 牙科医学
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是慢性肝病的主要原因.
- 除了牙周炎之外,口腔健康因素在MASLD中还没有得到充分的研究.
- 未经治疗的牙损伤和未得到满足的牙护理需求将根据新的MASLD标准进行检查.
研究的目的:
- 评估美国成年人口腔健康指标和MASLD之间的关联.
- 探索在MASLD中未经治疗的虫和牙护理需求的作用.
- 评估这些关联中的潜在的性别特异性差异.
主要方法:
- 从NHANES (2017-2020) 分析了2528名美国成年人的肝脏过渡性弹性图.
- MASLD 定义为脂肪 (≥285 dB/m) 和≥1代谢风险因子.
- 对社会人口统计学和行为因素进行调整后的物流回归.
主要成果:
- 患MASLD的流行率为38.9%.
- 需要牙科护理 (OR=1.42) 和腐烂的牙 (OR=1.52) 与更高的MASLD几率有关.
- 在妇女和老年人中观察到更强烈的关联;经过校正后,牙科护理需求仍然很大 (q=0.043).
结论:
- 未满足的牙需求和牙与MASLD有关.
- 口腔健康是MASLD风险的潜在标志物.
- 综合口腔系统性评估对于预防性护理非常有价值.
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