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Updated: Jan 31, 2026

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克服质母细胞瘤内在和获得的temozolomide耐药性:通过ZEB1调节来增强敏感性的潜在策略是fisetin

Sena Ferah1, Mine Çamlıbel1, Melis Erçelik1

  • 1Bursa Uludağ University Faculty of Medicine, Department of Medical Biology, Bursa, Türkiye.

Turkish journal of pharmaceutical sciences
|January 30, 2026
PubMed
概括

生物黄素fisetin通过减少细胞增殖和克服TMZ耐药性来增强temozolomide (TMZ) 对质母细胞瘤 (GB) 的疗效. 这种组合疗法显示出改善质母细胞瘤治疗结果的希望.

关键词:
质母细胞瘤 (glioblastoma) 是一个在ZEB1中,ZEB1是指ZEB1.表皮细胞到介质细胞的过渡.素是素中的一种成分.泰莫索洛米德的耐药性

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