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Updated: Jan 31, 2026

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在患有非典型局部脂质变症的患者中发现的EBF2变体会导致脂肪纤维化和功能障碍

Maria C Foss-Freitas1, Donatella Gilio1, Lynn Pais2

  • 1Caswell Diabetes Institute and Metabolism, Endocrinology and Diabetes Divis, University of Michigan Medical School, Ann Arbor, United States of America.

The Journal of clinical investigation
|January 30, 2026
PubMed
概括

早期B细胞因子2 (EBF2) 的遗传变异通过损害脂肪组织发育和重塑而导致脂质变异. 这种EBF2干扰导致代谢功能障碍,包括胰岛素抵抗和葡萄糖不耐受.

关键词:
脂肪组织的脂肪组织.遗传变异是一种遗传变异.遗传学 遗传学 是一个代谢过程中的代谢.转录 转录 转录 转录

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