焦点肺病变的CT指导核心针活检与共存的间歇性肺异常:一个病例控制研究
Maurizio Balbi1, Luisella Righi2, Noemi Cristina Culasso3
1Radiology Unit, San Luigi Gonzaga Hospital, Department of Oncology, University of Turin, Orbassano, Italy. maurizio.balbi@unito.it.
European radiology
|January 30, 2026
概括
通过CT指导的核心针活检 (CNB) 是安全而准确的,用于诊断患有间歇性肺异常 (ILA) 患者的肺病变. 在穿越ILA或执行多个胸腔通行时,并发症的风险会增加.
科学领域:
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
- 干预性肺病学 干预性肺病学
背景情况:
- 间歇性肺异常 (ILAs) 可以使焦点肺病变的诊断复杂化.
- 用CT指导的核心针活检 (CNB) 是诊断肺病变的常见工具.
研究的目的:
- 评估CT导向CNB在患有焦点肺病变和同时存在的ILA的患者的安全性和诊断性能,与没有ILA的患者相比.
- 在CT指导的CNB中确定并发症和非诊断样本的预测因子,用于患有ILA的患者.
主要方法:
- 一个追溯的1:1匹配病例对照研究,比较了接受CT指导CNB的ILA患者和对照患者.
- 对并发症的分析,样本的充分性和恶性瘤的诊断准确性.
- 后勤回归用于识别并发症预测因子.
- 在切除病例中对非新发性肺组织进行组织病理学审查.
主要成果:
- 在整体并发症,重大/轻微并发症,非诊断样本或诊断性能 (准确性,敏感性,特异性) 之间没有显著差异.
- 针穿过ILAs和多个气通道与增加的并发症风险有关.
- 在ILA中,非瘤性肺部显示出更复杂的组织学和纤维状特征.
结论:
- CT指导的CNB是一种安全而准确的方法,用于诊断患有同时存在ILA的患者的焦点肺病变.
- 尽量减少ILA穿越和限制胸腔通道可以降低并发症率.
- 对于ILA患者来说,CNB仍然是一个有价值的诊断程序.
相关概念视频
01:14Imaging Studies I: CT and MRI
866
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
866
02:10The Nucleosome Core Particle
14.4K
Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
14.4K
01:28Imaging Studies for Cardiovascular System V: CT
360
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
360
01:47Lung Capacity
56.3K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.3K
02:23Abnormal Proliferation
5.2K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.2K
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
480
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
480