相关实验视频
Updated: Jan 31, 2026

08:43
Orthotopic Mouse Model of Colorectal Cancer
Published on: December 4, 2007
47.2K
在智障人士中进行结肠直肠癌查
Trine Allerslev Horsbøl1, Susan Ishøy Michelsen1, Trine Toft Sørensen1
1National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
JAMA network open
|January 30, 2026
概括
智力障碍 (ID) 患者的结直肠癌查参与率和完成率较低. 需要量身定制的战略来解决这些差异,并改善ID患者获得癌症查的平等机会.
科学领域:
- 公共卫生 公共卫生
- 癌症查 癌症查
- 健康差异 在健康上的差异
背景情况:
- 结肠直肠癌 (CRC) 死亡率在智力障碍 (ID) 患者中较高,可能是由于诊断延迟.
- 有效的CRC查对于早期检测和改善结果至关重要.
研究的目的:
- 为了比较具有和没有ID的个人之间的CRC查参与率和完成率.
- 确定ID患者查过程中的潜在障碍和差异.
主要方法:
- 在丹麦 (2014-2023) 进行全国范围的基于登记的队列研究.
- 邀请50-74岁居民参加两年一度的CRC查.
- 具有和没有ID的个体之间的查参与 (便样本返回) 和完成 (诊断检查) 的比较,根据残疾严重程度进行调整.
主要成果:
- 与没有ID的人相比,ID患者在CRC查中的参与率 (30.2%对56.1%) 和诊断检查完成率 (70.5%对90.2%) 显著降低.
- 随着智力障碍的严重程度的增加,参与率和完成率下降.
- 便样本采集和结肠镜检查的困难在ID患者中更为常见.
结论:
- 智障人士在参与和完成结直肠癌查时面临重大障碍.
- 查参与和完成的差异凸显了需要量身定制的决策支持策略,以确保公平的癌症护理.
- 解决这些差异对于降低ID人口中的结直肠癌死亡率至关重要.
相关概念视频
Intellectual Disability
738
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
738
Learning Disabilities
611
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
Dyslexia
Dyslexia is a...
611
Genetic Screens
5.7K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.7K
Cancer
54.2K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
54.2K
What is Cancer?
14.4K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
14.4K
Cancer Vaccines
1.0K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.0K

