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Updated: Feb 1, 2026

An In Vivo Mouse Model to Measure Naïve CD4 T Cell Activation, Proliferation and Th1 Differentiation Induced by Bone Marrow-derived Dendritic Cells
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An In Vivo Mouse Model to Measure Naïve CD4 T Cell Activation, Proliferation and Th1 Differentiation Induced by Bone Marrow-derived Dendritic Cells

Published on: August 22, 2018

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在慢性病毒感染期间,从前体中间体的逐步分化和独特的Th1检查点促进CD4Th1细胞分化

Hongshen Niu1,2, Siying Lin1,2,3, Ryan Brown1,2,3

  • 1Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.

Proceedings of the National Academy of Sciences of the United States of America
|January 30, 2026
PubMed
概括

准PD-1/PD-L1信号和PBAF复合体可以恢复CD4+ T辅助1细胞的功能. 这种方法通过改善T辅助1细胞的分化和维护来增强慢性感染期间的病毒控制.

关键词:
CD4+ T 细胞是 CD4+ T 细胞.在 LCMV 中,LCMV 是Th1差异化的差异化染色体重塑 染色体重塑的方法免疫疗法 免疫疗法

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