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Updated: Feb 1, 2026

Use of a Monocyte Monolayer Assay to Evaluate Fcγ Receptor-mediated Phagocytosis
06:27

Use of a Monocyte Monolayer Assay to Evaluate Fcγ Receptor-mediated Phagocytosis

Published on: January 2, 2017

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跨物种细胞映射和Fcγ受体的人性化,以推进抗体建模

Karel F A Van Damme1,2, Dorine Sichien1,2,3, Katrien Van der Borght1,2,4,5

  • 1Laboratory of Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, Belgium.

Science immunology
|January 30, 2026
PubMed
概括

这项研究绘制了跨物种的Fc玛 (Fcγ) 受体表达图,揭示了影响抗体研究模型的差异. 一只具有人类Fcγ受体和FcRn的新型人性化小鼠改善了临床前抗体评估.

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