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Updated: Feb 1, 2026

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
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KPC-2 的酸盐敏感性:β-乳酸酶动态中的一个隐藏变量

Dignite F Ngango1, André Birgy1,2, Timothy Palzkill1

  • 1Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas, USA.

Antimicrobial agents and chemotherapy
|January 30, 2026
PubMed
概括

酸盐缓冲剂通过与活性部位结合来抑制KPC-2β-乳糖酶活性,从而减少抗生素耐药性评估. 这种酶特异性效应凸显了在β-乳糖酶试验中需要仔细选择缓冲区的必要性.

关键词:
抗生素耐药性 抗生素耐药性贝塔乳酸抗生素的抗生素是贝塔乳酸抗生素.贝塔-乳糖酶是一种酵素学 酵素学 酵素学

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