调查创伤后应激障碍和REM睡眠行为障碍之间的关联:系统性审查
Valentina Baldini1, Martina Gnazzo2, Giorgia Varallo2
1Department of Biomedical and Neuromotor Sciences, University of Bologna, Italy; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy.
Sleep medicine reviews
|January 30, 2026
概括
创伤后应激障碍 (PTSD) 与较高的REM睡眠行为障碍 (RBD) 患病率有关,特别是在退伍军人中. 临床上建议对PTSD患者进行RBD评估,反之亦然.
科学领域:
- 精神病学是一个精神病学.
- 睡眠医学 睡眠医学
- 神经学 神经学
背景情况:
- 创伤后应激障碍 (PTSD) 经常与失眠和梦等睡眠障碍同时发生.
- 新出现的证据表明,PTSD和REM睡眠行为障碍 (RBD) 之间存在潜在联系.
研究的目的:
- 系统地审查和评估有关PTSD和RBD之间关系的现有证据.
- 检查PTSD-RBD协会的流行率,诊断方法,共享机制和临床影响.
主要方法:
- 在主要数据库 (PubMed,科学网,EMBASE,PsycINFO) 进行了全面的文献搜索,截至2025年7月.
- 包括的研究是观察性,队列和实验性设计,评估PTSD患者的RBD.
- 使用纽卡斯尔-太华尺度评估方法质量.
主要成果:
- 七项涉及4152名参与者的研究符合纳入标准.
- 创伤后应激障碍与可能或确诊的RBD患病率明显增加有关,特别是在老兵群体中.
- 与其他异常睡眠症相比,患有孤立RBD的个体更有可能患上并发性PTSD.
- 与PTSD相关的RBD与增加的精神病理相关,包括抑郁症,梦和情绪失调.
结论:
- 在PTSD和RBD之间存在着显著的关联,在PTSD患者中患病率更高.
- 临床实践应包括对患有偏睡症的PTSD患者进行RBD查,以及对具有梦想行为行为的人进行PTSD查.
- 对共享的病理生理机制的进一步研究可能会阐明并发性疾病的治疗策略.
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