在心脏起器诱导的心肌病的导电系统节奏之后,心电图复极变化发生变化
Ahmet Taha Sahin1, Ugur Canpolat2, Muhammet Dural3
1Department of Cardiology, Necmettin Erbakan University Hospital, Meram, Konya, Turkiye.
Journal of electrocardiology
|January 30, 2026
概括
左捆支部区域节奏 (LBBAP) 在患有心脏起器诱导心肌病症 (PICM) 的患者中没有不利的复极效应. 这种生理节奏策略是安全的,可以与扩张性心肌病 (DCM) 控制相比较.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 医疗器械 医疗器械
背景情况:
- 心脏起器诱导的心肌病 (PICM) 是由慢性右心室节奏 (RVP) 引起的,导致左心室功能障碍.
- 左捆分支区域节奏 (LBBAP) 是一种生理节奏策略,可以逆转PICM.
- 在PICM中,LBBAP对心室复极化的急性影响尚不清楚.
研究的目的:
- 在PICM患者中评估LBBAP后立即复极化变化.
- 为了将接受LBBAP的PICM患者的复极化反应与非缺血性扩张性心肌病 (DCM) 患者的对照组进行比较.
主要方法:
- 对接受成功LBBAP的患者的临床,心电图和节拍数据的回顾性分析.
- 手动测量基线和植入后心电图间隔 (QT,QTc,Tp-Te) 和T波记忆 (TWM) 的定性评估.
- 记录程序参数,成功率和并发症.
主要成果:
- 包括60名患者 (28名PICM,32名DCM);基线LVEF在PICM中较高.
- 在不同组中,LBBAP的成功率相似 (93%对96%).
- PICM患者的QRS速度更快,V6-V1间隔更长,但复极化指标 (QT,QTc,Tp-Te,TWM) 显示没有不良变化,与DCM对照可比.
结论:
- 在PICM中,LBBAP不会诱导不利的急性再极化变化.
- 在PICM中LBBAP后的再极化反应与DCM患者的反应相似.
- LBBAP支持安全性,并证明了PICM升级的生理益处.
相关概念视频
Cardiomyopathy II: Dilated Cardiomyopathy
566
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
566
Cardiomyopathy III: Hypertrophic Cardiomyopathy
488
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
488
Cardiomyopathy IV: Restrictive Cardiomyopathy
532
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
532
Cardiomyopathy V: Interprofessional Care
442
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
442
Cardiomyopathy I: Introduction and Classification
605
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
605
Cardiomyopathy VI: Nursing Management
354
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
354


