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Updated: Feb 1, 2026

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在癌症治疗中,KRAS抑制剂的新兴景观

Jakob M Riedl1, Hiroyuki Matsubara2, Reid McNeil2

  • 1Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA, USA; Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

Cancer cell
|January 30, 2026
PubMed
概括

在癌症中,RAS通路突变很常见. 虽然KRAS G12C抑制剂显示出前景,但耐药性限制了有效性. 下一代抑制剂旨在克服耐药性,并为更多患者提供更广泛的治疗效益.

关键词:
克拉斯 (Kras) 是一个国家.在KRAS G12C中使用.这是一种KRAS抑制剂.结肠直肠癌是什么意思药物耐药性 耐药性 药物耐药性非小细胞肺癌的肺癌.胰腺癌是一种癌症.

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