COVID-19增加了老年人部骨折的风险 - - 一项基于登记的瑞典人口研究
Kristina Kajba1, Yiyi Xu2, Ailiana Santosa2
1School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Bone
|January 30, 2026
概括
感染COVID-19显著增加关节骨折的风险,特别是在男性和65岁以上的成年人. 这凸显了在COVID-19后需要有针对性的骨折预防策略.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 老年医学 老年医学
背景情况:
- 关节骨折是一个重大的公共卫生挑战,导致严重的发病率和死亡率.
- COVID-19对骨折风险的潜在影响仍然是积极调查的领域.
研究的目的:
- 调查COVID-19感染与瑞典成年人部骨折风险之间的联系.
- 根据性别和年龄来检查这种关联中的差异.
主要方法:
- 研究人员对3,931,893名年龄≥50岁的瑞典居民进行了基于人口的队列研究.
- 通过国家登记册确定了COVID-19病例,并记录了关节骨折的发生率.
- 考克斯比例危险回归模型被用来估计危险比率,调整各种共变量.
主要成果:
- COVID-19与43%的部骨折风险增加有关 (HR 1.43).
- 这种风险在男性 (HR 1.57) 比女性 (HR 1.36) 更高.
- 在65岁以上的个体中观察到显著的关联,但在50-65岁的人中没有.
结论:
- COVID-19感染与关节骨折风险显著增加有关,特别是在老年人 (≥65岁).
- 这些发现强调,在COVID-19感染后,老年人群中需要采取专注的骨折预防措施.
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