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Updated: Feb 1, 2026

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
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LCA和3-oxo-LCA减轻了肠道上皮细胞中饮食氧化醇诱导的屏障功能的丧失

Gayatri Reghu1, Ashna Fathima1, Narendran Swaminathan1

  • 1Cell Signaling Laboratory, Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Hyderabad Campus, Jawahar Nagar, Kapra Mandal, Medchal District, Telangana 500078, India.

Steroids
|January 30, 2026
PubMed
概括

饮食中的氧化会通过增加MMP和炎症来损害肠道屏障的完整性. 然而,二次胆汁酸,石化胆汁酸 (LCA) 和3-oxo-LCA,恢复了屏障功能,并减少了氧化醇引起的肠细胞损伤.

关键词:
饮食中摄入的氧醇是肠道上皮细胞是肠道上皮细胞.矩阵金属蛋白酶是一种金属蛋白酶.二次胆汁酸二次胆汁酸二次胆汁酸紧密结合蛋白质是紧密结合的蛋白质.

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