早期宫长度查和自发早产的种族和民族差异
Jamie A Green1, Frank I Jackson1, Sarah H Abelman1
1Northwell, New Hyde Park, NY; Department of Obstetrics and Gynecology, South Shore University Hospital, Bay Shore, NY; Zucker School of Medicine, Hempstead, NY.
American journal of obstetrics & gynecology MFM
|January 30, 2026
概括
在早产中存在种族差异,但早期的宫长度查和 cerclage 放置似乎减少了结果差异. 公平地实施这些干预措施是减少差距的关键.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 健康差距 研究 研究 研究 研究
背景情况:
- 在早产率上持续存在的种族和民族差异凸显了研究预防策略的必要性.
- 宫长度查和 cerclage 放置是自发早产 (sPTB) 的确立干预措施,但它们的公平使用尚不清楚.
研究的目的:
- 调查早期宫长度查和 cerclage 放置的利用种族和民族差异.
- 评估这些干预措施对不同种族和种族群体的早产结果的影响,在有史以来sPTB的患者中.
主要方法:
- 追溯性队列研究,对924名有sPTB病史的患者进行.
- 早期宫长度查 (16-18周妊娠) 和 cerclage 放置的分析.
- 多变量后勤回归调整为社会人口统计学和临床因素.
主要成果:
- 与非西班牙裔白人患者相比,非西班牙裔黑人患者的早期查和 cerclage 放置的几率更高.
- 患者以前的sPTB<34周有显著增加接受查和 cerclage 的几率.
- 虽然总体上存在早产的差异,但在接受早期宫长度查的患者中没有观察到这些差异.
结论:
- 在高风险人群中观察到查和 cerclage 放置的种族和民族差异.
- 早期的子宫长度查和指定的 cerclage 放置的公平应用可以减轻早产后果的种族和民族差异.
- 基于证据的干预措施的持续实施对于减少早产差异至关重要.
相关概念视频
Spontaneity
29.8K
A spontaneous process is one that occurs naturally under certain conditions. A nonspontaneous process, on the other hand, will not take place unless it is “driven” by the continual input of energy from an external source. Processes have a natural tendency to occur in one direction under a given set of conditions. Water will naturally flow downhill (spontaneous process), but uphill flow (nonspontaneous process) requires outside intervention such as the use of a pump. Iron exposed to...
29.8K
Birth Control Methods
6.8K
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
6.8K
Ethnic Identity within a Larger Culture
338
Adolescents from ethnic minority backgrounds face a multifaceted journey in forming their identities, shaped by the intersections of cultural expectations and personal exploration. For these adolescents, identity formation involves not only typical developmental challenges but also navigating the perceptions and attitudes of the majority culture. As they grow, adolescents in ethnic minority groups often become increasingly aware of stereotypes, social biases, and discrimination, all of which...
338
Spontaneous and Induced Mutations
2.3K
Spontaneous mutations arise infrequently during DNA replication due to errors in the process. A key factor behind these errors is tautomeric shifts in nitrogenous bases, where bases transition from keto to enol forms or amino to imino forms. This shift can alter base-pairing rules, leading to mutations. Additionally, reactive oxygen species (ROS) arising from aerobic metabolism can damage DNA, resulting in depurination (loss of a purine base) or depyrimidination (loss of a pyrimidine base).
2.3K
Genetic Screens
5.7K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.7K
Attitudes
33.2K
Attitude is our evaluation of a person, an idea, or an object. We have attitudes for many things ranging from products that we might pick up in the supermarket to people around the world to political policies. Typically, attitudes are favorable or unfavorable: positive or negative (Eagly & Chaiken, 1993). And, they have three components: an affective component (feelings), a behavioral component (the effect of the attitude on behavior), and a cognitive component (belief and knowledge;...
33.2K


