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Updated: Feb 1, 2026

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
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Published on: May 20, 2016

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合理化鼻至脑药物输送:以机器学习为指导,优化和机械阐明鼻喷雾的嗅觉沉积

Zizhao Zhai1, Wenhao Wang2, Guanlin Wang2

  • 1State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, Jinan University, Guangzhou 510632, Guangdong, PR China; College of Pharmacy, Jinan University, Guangzhou 510632, Guangdong, PR China.

Journal of controlled release : official journal of the Controlled Release Society
|January 30, 2026
PubMed
概括

使用机器学习优化固体脂质纳米粒子鼻喷雾 (SLN-NS) 显著提高了嗅觉沉积. 这提高了神经系统疾病,如阿尔茨海默氏症和帕金森病的药物输送.

关键词:
分散的介质分散的介质.机器学习 机器学习鼻子到大脑的药物输送.嗅觉沉积的沉积是一种嗅觉沉积.固体脂质纳米粒子 固体脂质纳米粒子

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