围产期和产妇结局,按第二个三个月的分娩指示划分
Kristen Cagino1, Paula McGee2, Maged M Costantine3
1Obstetrics and Gynecology, University of Texas McGovern Medical School, Houston, United States.
American journal of perinatology
|January 30, 2026
概括
严重预先分娩症 (PE-SF) 的第二季度早产显示出更高的胎儿死亡率,而不是早产早产膜破裂 (PPROM). 综合新生儿和孕产妇发病率在这些早产症候群之间没有差异.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿科学 新生儿科学
- 围产儿医学 围产儿医学
背景情况:
- 在早产中,围产和母亲的结果可以根据分娩的原因而有所不同.
- 严重的孕前 (PE-SF) 和早产前膜破裂 (PPROM) 是第二季度早产的常见症状.
研究的目的:
- 为了比较PE-SF与PPROM显示的第二个三个月分娩之间的产周和产妇结局.
- 确定与早产早产的每个分娩指示相关的特定风险.
主要方法:
- 一项观察性队列研究的二次分析,该研究涉及35周怀孕前单子和双胞胎过早分娩.
- 包括没有先天性异常的独生子,由于PE-SF或PPROM而在妊娠24 0/7至27 6/7周之间出生.
- 主要结局是围产期发病率或死亡的复合;次要结局包括小于妊娠年龄 (SGA) 的出生和孕产妇发病率.
主要成果:
- 对于PE-SF的分娩,更有可能与更高的BMI,先前的高血压障碍,慢性高血压和剖腹产有关.
- 在PE-SF和PPROM组之间,复合周产期发病率或死亡率没有显著差异.
- 胎儿死亡率在PE-SF组显著高 (aOR 6.04),新生儿更有可能患有SGA (aOR 13.45).
结论:
- 与PPROM出生相比,对于PE-SF的第二个三个月的早产与胎儿死亡的风险增加有关.
- 综合新生儿发病率和孕产妇发病率在两种适应症之间没有显著差异.
- 产后指示在早产早产的特定围产期结果中起作用.
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