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Updated: Feb 1, 2026

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
08:11

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使用OCT进行视觉神经成像预测疾病进展,并监测原发性渐进性多发性硬化症中大脑和脊髓缩

Luca Bollo1, Deborah Pareto2, Paula Tagliani1

  • 1Multiple Sclerosis Center of Catalonia (Cemcat) and Department of Neurology Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

Multiple sclerosis (Houndmills, Basingstoke, England)
|January 30, 2026
PubMed
概括

在原发性渐进性多发性硬化症 (PPMS) 中,更薄的周状视网膜神经纤维层 (pRNFL) 预测了更快的残疾进展和增加的神经退行. 这一发现支持pRNFL作为PPMS临床试验中的关键生物标志物.

关键词:
光学连贯性断层扫描 (OCT)这是一个PPMSPPMS.在pRNFL中,

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