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Updated: Feb 1, 2026

In Ovo Xenografting of Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells (PDX-ALL)
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mTOR调节影响KMT2A重新排列的急性淋巴细胞白血病细胞中的galactin-1表达

Bartłomiej Pawlik1,2, Joanna Madzio1, Zuzanna Rydzyńska1

  • 1Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland.

Anticancer research
|January 30, 2026
PubMed
概括

针对mTOR途径可以调节KMT2A重组的急性淋巴细胞白血病 (KMT2A r-ALL) 中的免疫检查点蛋白 Galectin-1. 这一发现表明mTOR抑制是针对KMT2A r-ALL.免疫逃避的潜在策略.

关键词:
盖莱克-1是一种KMT2A-重新安排的MLL-重新安排的MLL.急性淋巴细胞白血病急性淋巴细胞白血病在mTOR信号通道上.

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