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临床特征和影响疹简单角膜炎患者视觉结果的因素:第三级医院的经验
H Najiza1,2, J Muhammed3,2
1Department of Ophthalmology and Visual Science, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
The Medical journal of Malaysia
|January 30, 2026
概括
马来西亚的疹简单角膜炎 (HSK) 呈现出常见的症状,如视力减弱和红色. 诸如老年和中部角膜干扰等因素预测视觉结果较差,有助于临床管理.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 疹简单角膜炎 (HSK) 是全球感染性角膜失明的主要原因.
- 马来西亚HSK临床特征和视觉结果的数据有限.
- 本研究通过分析马来西亚一家三级医院的HSK病例来弥补这一差距.
研究的目的:
- 在马来西亚患者中确定HSK的常见临床特征.
- 为了评估HSK治疗后的视觉结果.
- 确定与HSK视觉预后相关的因素.
主要方法:
- 在马来西亚帕克大学科学医院对67名HSK患者进行了回顾性队列研究 (2013年6月至2024年6月).
- 数据包括人口统计,症状,最佳校正视敏度 (BCVA),眼部发现,HSK亚型和并发症.
- 统计分析涉及配对t测试和多重线性回归.
主要成果:
- 平均年龄为50.4岁,52.2%是男性. 大多数病例 (91.1%) 是单边的.
- 常见的症状包括视力低下 (89.6%) 和眼睛发红 (85.1%). 角膜炎是最常见的亚型 (37.3%).
- 并发症包括角膜痕 (73.1%) 和复发 (49.3%). 在治疗后,BCVA显著改善 (p<0.001). 年龄较大,中心参与,内压升高和肌体血管化预测结果较差.
结论:
- 本研究描述了马来西亚的HSK的临床形状和视觉结果.
- 视力差的预测因素包括老年,中枢角膜干扰,眼内压力升高和肌体血管化.
- 研究结果支持加强对HSK患者的风险分层和管理优化.
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