在ELSA-巴西研究中,长时间和短时间睡眠者的预测因素的异质性
Aline N Aielo1, Ronaldo B Santos2, Soraya Giatti3
1Centro de Pesquisa Clínica e Epidemiologica (CPCE), Universidade de Sao Paulo, Sao Paulo, Brazil.
Sleep health
|January 30, 2026
概括
老年和抑郁症与更长的睡眠时间有关,而男性性别,黑人种族,白天嗜睡和睡眠呼吸暂停预测睡眠时间更短. 这些因素对于了解睡眠时间的风险至关重要.
科学领域:
- 睡眠医学 睡眠医学
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 长时间的睡眠时间与心血管事件和死亡率的增加有关,但根本原因尚未完全理解.
- 识别异常睡眠时间的预测因素对于了解相关的健康风险至关重要.
研究的目的:
- 通过客观测量来研究与长 (主要) 和短 (次要) 睡眠时间相关的独立变量.
- 为了探索长睡眠时间 (≥8小时) 和短睡眠时间 (<6小时) 的预测因素,在一个大成年队列中.
主要方法:
- 利用了ELSA-巴西研究的数据,包括临床评估,睡眠问卷,针对阻塞性睡眠呼吸暂停 (OSA) 的家庭睡眠监测,以及针对睡眠持续时间 (SDUR) 的7天行为摄影.
- 采用多项回归分析来确定长期和短期SDUR的预测因子,参考组为6至8小时以下.
主要成果:
- 该研究包括2062名参与者 (平均年龄49±8岁,57.3%是女性);三分之一的人患有OSA. 平均SDUR为6.55 ± 0.49小时.
- 长期持续时间 (≥8小时) 独立地与老年 (OR=1.36) 和抑郁症 (OR=2.59) 相关.
- 短SDUR (<6小时) 与男性性别 (OR=1.9),黑人参与者 (OR=1.75),过度白天嗜睡 (OR=1.49) 和OSA (OR=1.48) 相关.
结论:
- 在一个大型的多民族群体中,长时间和短时间睡眠的预测因素存在显著的异质性.
- 诸如老年和抑郁症等因素可能导致长时间睡眠者心血管风险增加.
- 确定睡眠时间短暂的特定预测因素,包括OSA和白天嗜睡,对于有针对性的干预至关重要.
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