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Updated: Feb 1, 2026

Testing the In Vitro and In Vivo Efficiency of mRNA-Lipid Nanoparticles Formulated by Microfluidic Mixing
08:55

Testing the In Vitro and In Vivo Efficiency of mRNA-Lipid Nanoparticles Formulated by Microfluidic Mixing

Published on: January 20, 2023

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核心脂纳米颗粒的工程内部架构促进了高效的mRNA内体释放

Tianyao Li1,2, Jingxin Zhang1,3, Jing Guo4

  • 1CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Chinese Academy of Sciences (CAS), Beijing, China.

Nature communications
|January 30, 2026
PubMed
概括

新的脂质纳米颗粒 (LNP) 与金纳米颗粒核心通过增强内体逃生来改善信使RNA (mRNA) 传递. 这一突破提高了mRNA表达和治疗疗效,用于疫苗和癌症治疗.

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