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Updated: Feb 1, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
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针对C5aR的LukS-PV通过BCL6/HDAC6/HSPD1轴抑制肝细胞癌中的EMT

Pengsheng Ding1, Lan Shi1, Xuexue Xu2

  • 1Department of Clinical Laboratory, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Communications biology
|January 30, 2026
PubMed
概括

黄金葡萄球菌分泌的LukS-PV向C5a受体 (C5aR),以抑制肝细胞癌 (HCC) 细胞转移. 这种新的治疗方法影响BCL6/HDAC6/HSPD1通路,为HCC治疗提供了潜力.

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