肺外结核:移民和出生在发病率低的国家的人口之间的比较
C R Khaw1, A M Malhotra2, S Tehranchi3
1Department of Respiratory Medicine, University College London, London, UK;, Respiratory Medicine Department, Barts Health NHS Trust, London, UK.
概括
肺外结核 (EPTB) 在英国越来越常见,特别是在移民中. 这项研究发现,东伦敦的EPTB负担更高,移民的治疗结果更差,主要是由于死亡率增加.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 在像英国这样的高收入国家,非肺结核 (EPTB) 的比例正在上升.
- 伦敦东部,有着多元化的移民人口和高结核病发病率,是EPTB研究的独特焦点.
研究的目的:
- 调查伦敦东部EPTB的负担和特征.
- 将该地区的EPTB患病率与国家数据进行比较.
- 分析移民身份与EPTB之间的关联.
主要方法:
- 东伦敦2016年至2019年期间诊断的结核病例的回顾性分析.
- 将当地EPTB数据与国家结核病统计数据进行比较.
- 多变量分析以评估移民与英国出生的人口中EPTB的几率.
主要成果:
- 在1,262例结核病例中,超过一半 (52.7%) 是EPTB,超过了全国单独的EPTB率43.8%.
- 非英国出生的个人 (移民) 占EPTB病例的83.6%,并且患EPTB的几率明显更高 (aOR: 1.55).
- 被诊断为EPTB的移民自进入英国以来平均有11年时间,并经历了较差的治疗结果,包括较高的死亡率.
结论:
- 东伦敦的EPTB比例高于全国平均水平.
- 该地区的移民人口不成比例地受到EPTB的影响.
- 移民社区可能需要有针对性的公共卫生干预措施来解决结核病治疗结果的差异.
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