与瘤相关的巨细胞在细胞外囊中显示差异性蛋白质载荷分类,与卵巢癌的生存率差相关

Johanna Pörschke1, Sophie Heidemann2, Hannah P Nehring1,3

  • 1Institute for Tumor Immunology, Center for Tumor Biology and Immunology (ZTI), Philipps-Universität, Marburg, 35043, Germany.

概括

卵巢癌的瘤相关巨细胞 (TAMs) 释放出具有独特蛋白质载荷的独特的细胞外囊泡 (EVs). 这些TAM衍生的EV携带与预后不佳相关的生物标志物,提供新的诊断和治疗点.

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