用"维生素C诱导的休眠Mtb"THP-1细胞感染模型对宿主对"休眠"Mycobacterium结核病的反应进行洞察

Kiran Kumari1, Sakshi Dhingra Batra1, Kriti Sikri1,2

  • 1Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India.

BMC genomics
|January 30, 2026
PubMed
概括

了解宿主对休眠的Mycobacterium结核病 (Mtb) 的遗传反应是对抗潜在结核病的关键. 这项研究揭示了Mtb感染如何改变宿主通路,影响免疫监测,DNA修复和亡,最终有利于细菌的持久性.

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