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Updated: Feb 1, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
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Published on: March 26, 2018

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在急性髓性白血病中,SRSF2突变通过THBS1稳定驱动了多诺鲁比辛耐药性

Wu Ye1,2, Xia Wu1, Yuqian Tang1

  • 1Department of Hematology, West China Hospital, Sichuan University, No.37 GuoXue Xiang, Chengdu, 610041, Sichuan Province, China.

Journal of experimental & clinical cancer research : CR
|January 31, 2026
PubMed
概括

在急性髓性白血病 (AML) 中的SRSF2突变降低了生存率和化疗的有效性. 针对PDGFB途径使用达诺鲁比为具有这些突变的AML患者提供了潜在的新治疗策略.

关键词:
在SRSF2突变中.急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.细胞代谢的细胞代谢.化学疗法耐药性 抗化学疗法耐药性有协同效应的效应.

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