格陵兰的B,C和Delta病毒性肝炎:一项全国跨部门研究
Carina Nørskov Naustdal1,2,3, Gerda Elisabeth Villadsen4,5, Karsten Fleischer Rex6,7
1Queen Ingrid's Hospital, Center of Primary Health Care, Nuuk, Greenland.
Journal of viral hepatitis
|January 31, 2026
概括
更新的数据显示,格陵兰的B型和C型病毒性肝炎的流行率很低. 然而,D型肝炎病毒的同时感染在乙型肝炎患者中很常见,需要提高意识和监测.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 北极健康 北极健康
背景情况:
- 病毒性乙型肝炎 (HBV) 是北极地区的流行病.
- 公共卫生干预后需要更新的流行病学数据.
- 慢性病毒性型肝炎 (HCV) 和三角型肝炎 (HDV) 也需要调查.
研究的目的:
- 确定格陵兰的慢性HBV,HCV和HDV的流行率和疾病特征.
- 在几十年的查,疫苗接种和治疗计划之后,评估当前的感染率.
主要方法:
- 从2014年到2023年使用电子医疗记录进行全国范围的横截面研究.
- 根据血清学和分子标志物识别HBV,HCV和HDV的患者.
- 对人口统计数据,肝脏生物化学和纤维化-4 (FIB4) 评分的分析.
主要成果:
- 发现HBV (0.53%) 和HCV (0.08%) 的低患病率.
- 在9.4%的HBV患者中发现了HDV同时感染,其中82%具有活跃的HDV-RNA感染.
- 与HBV患者 (9%) 相比,HCV患者的肝酶略有升高,FIB4得分升高的比率更高 (36%),HBV患者的比率更高 (9%).
结论:
- 目前在格陵兰的HBV和HCV发病率很低,低于以前报告的人口查研究.
- 在HBV患者中,高密度病毒的同时感染是常见的,表明正在进行的传播,需要提高临床意识.
- 虽然很少见,但HCV病例需要监测肝酶和纤维化进展.
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