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Updated: Feb 1, 2026

Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo
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Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo

Published on: June 2, 2019

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在受控封闭条件下的α-Synuclein纤维中的蛋白质结构和合溶剂动力学

Katie Lynn Whitcomb1, Kurt Warncke1

  • 1Department of Physics, Emory University, Atlanta, Georgia, 30322.

Biophysical journal
|January 31, 2026
PubMed
概括

帕金森病的蛋白质α-synuclein纤维呈现动态障碍. 限制和温度变化揭示了蛋白质的崩和折叠,为针对这些纤维的药物开发提供了洞察力.

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