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相关概念视频

Quality Control01:05

Quality Control

2.5K
Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
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Drug Binding to Blood Components01:30

Drug Binding to Blood Components

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When drugs enter systemic circulation, they interact with various components of the blood, including proteins such as human serum albumin (HSA), α1-acid glycoprotein (AAG), lipoproteins, globulins, and red blood cells (RBCs).
HSA is the most abundant plasma protein and is vital in drug binding. It contains distinct drug-binding sites, with different drugs exhibiting affinity for specific sites. There are three main drug-binding domains for HSA: sites I, II, and III. These domains are...
532
Components of Stress01:23

Components of Stress

536
Stress analysis under multiple loading conditions is intricate, necessitating a comprehensive grasp of normal and shearing stresses. Consider a small cube at point O, subjected to stress on all six faces, visible or not. Normal stress components σx, σy, σz act perpendicularly to the x, y, and z axes. Shearing stress components τxy and τxz are exerted on faces perpendicular to these axes.
Interestingly, the hidden cube faces also experience these stresses, equal and...
536
Components of Language01:24

Components of Language

820
Language, whether spoken, signed, or written, consists of specific components: lexicon and grammar. The lexicon is the vocabulary of a language, comprising its words. Grammar is the set of rules used to convey meaning through the lexicon. For example, English grammar adds “-ed” to most verbs to indicate past tense. Words are formed by combining phonemes, which are the basic sound units of a language. Different languages have different sets of phonemes (e.g., “ah” vs.
820
The Cell Cycle Control System01:28

The Cell Cycle Control System

5.6K
The cell cycle regulation directs how a cell proceeds from one phase to the next and begins mitosis. The cell cycle control system includes intracellular regulatory molecules and external triggers. They provide "stop" or "advance" signals and operate at specific cell cycle stages termed checkpoints to ensure that a particular process is completed before the cell advances to the next phase.
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
5.6K
The Cell Cycle Control System02:11

The Cell Cycle Control System

14.3K
The cell cycle is an organized set of events that leads the cell to divide into two daughter cells, each containing chromosomes identical to the parent cell. It is the cell cycle that leads to the formation of an entire organism from a single-cell zygote. Besides, cell division also functions in the renewal or repair of tissues in adult multicellular eukaryotes. For example, in the bone marrow, the stem cells divide to form new blood cells. Although essential for several functions, cell...
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相关实验视频

Updated: Feb 1, 2026

Automated Quantification and Analysis of Cell Counting Procedures Using ImageJ Plugins
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Automated Quantification and Analysis of Cell Counting Procedures Using ImageJ Plugins

Published on: November 17, 2016

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自动细胞计数用于血液成分质量控制.

Gemma Aran1,2, Silvia Torrents1,2, Margarita Blanco1

  • 1Laboratori Cel·lular - Banc de Sang i Teixits, Barcelona, Spain.

Transfusion
|January 31, 2026
PubMed
概括

与手动技术相比,XN-1000血液银行模式提供了一种自动化,可靠的方法来量化血液成分中的残留细胞,改善质量控制和实验室效率.

关键词:
血液组成部分 血液成分血液学分析仪 血液学分析仪质量控制质量控制质量控制剩余细胞 剩余细胞

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Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging
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Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging

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Determination of Mammalian Cell Counts, Cell Size and Cell Health Using the Moxi Z Mini Automated Cell Counter
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Determination of Mammalian Cell Counts, Cell Size and Cell Health Using the Moxi Z Mini Automated Cell Counter

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相关实验视频

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Automated Quantification and Analysis of Cell Counting Procedures Using ImageJ Plugins
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Automated Quantification and Analysis of Cell Counting Procedures Using ImageJ Plugins

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Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging
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Determination of Mammalian Cell Counts, Cell Size and Cell Health Using the Moxi Z Mini Automated Cell Counter
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科学领域:

  • 血液储存和输血医疗 输血医疗
  • 血液学 血液学 血液学
  • 实验室自动化 实验室自动化

背景情况:

  • 准确量化残留白细胞 (rWBC) 和红细胞 (rRBC) 对血液产品安全至关重要.
  • 传统的手动流细胞计用于残留细胞分析是劳动密集型的,容易变化.
  • XN-1000 血液银行 (BB) 模式为质量控制 (QC) 提供了一个自动化的替代方案.

研究的目的:

  • 为了验证XN-1000 BB模式用于血液组件的自动化QC.
  • 将XN-1000 BB模式的性能与标准手动方法进行比较.
  • 评估自动化残细胞量化的准确性和效率.

主要方法:

  • 验证XN-1000 BB模式的精度,线性和传递.
  • 在红细胞,血小板和血产品中检测残留细胞.
  • 将BB模式结果与手动流量细胞计和基于阻抗的分析对1000多个血液成分进行比较.

主要成果:

  • XN-1000 BB模式显示出高线性,可接受的精度,没有分析干扰.
  • 剩余红细胞 (rRBC) 值在BB模式下较高,但在规范范围内.
  • 血小板计数 (PLT-F) 在BB模式下始终较高,反映了真正的血小板含量,比阻抗方法更准确.

结论:

  • XN-1000 BB模式是血液成分QC的可靠和高效的自动化替代方案.
  • 这种自动化方法提高了实验室的吞吐量,并简化了QC的工作流程.
  • 实现了精确的残留细胞量化,提高了产品质量和输血安全.