穿皮左心房附属体关闭:设备的演变和扩大临床应用
Andrea Urbani1, Joseph Antoine Kheir1, Lukas Urbanek1
1Cardioangiologisches Centrum Bethanien (CCB) Frankfurt Am Main, Medizinische Klinik III, Agaplesion Markus Krankenhaus Frankfurt Am Main, Germany.
Expert review of medical devices
|January 31, 2026
概括
穿皮左心房尾关闭 (LAAC) 为无法使用抗凝剂的非膜心房动 (AF) 患者提供了一种重要的中风预防方法. 不断发展的设备和技术正在扩大LAAC.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械技术 医疗器械技术
背景情况:
- 穿皮左心房尾关闭 (LAAC) 是非膜心房动 (AF) 患者的关键中风预防策略,这些患者不能耐受长期的口服抗凝药.
- 由于设备技术的进步和操作员能力的提高,LAAC的临床实用性和采用正在增长.
研究的目的:
- 为提供当前和新兴的皮肤穿左心房尾关闭 (LAAC) 装置的最新审查.
- 综合主要临床试验和注册表中的比较证据.
- 探索扩大的临床应用和LAAC的未来方向.
主要方法:
- 在PubMed,Scopus和Web of Science进行了全面的文献搜索.
- 该审查综合了LAAC可用设备的数据,比较试验证据和注册结果.
- 专注于新的应用程序和创新的设备设计.
主要成果:
- 该审查涵盖了当代和新兴的LAAC技术.
- 总结了主要试验和注册表中的比较证据.
- 讨论了扩大临床用途,包括在患有慢性病,左心房附属体血栓或尽管服用抗凝药,但仍患有中风的患者中,以及与心房移除结合的手术中.
结论:
- 现在,LAAC正在进入一个新的阶段,它有可能扩大目前使用范围以外的适用范围.
- 安全性方面的改进,个性化的抗血栓策略和创新的设备 (例如,双密封,基于排除) 正在推动这种进化.
- 未来的研究将确定LAAC是否可以成为主流的中风预防疗法.
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