相关实验视频

Updated: Feb 1, 2026

In vivo and in vitro Studies of Adaptor-clathrin Interaction
17:14

In vivo and in vitro Studies of Adaptor-clathrin Interaction

Published on: January 26, 2011

15.0K

通过适配器c-Crk或Abi-1对c-Abl交易的洞察:结构形式,活动站点类型和多个SH3-PxxPxK/R交互

Tomoyuki Shishido1,2, Masahiro Fujihashi3

  • 1SeemeData Labs, Inc., Tokyo, Japan.

Genes to cells : devoted to molecular & cellular mechanisms
|January 31, 2026
PubMed
概括

这项研究揭示了c-Abl激酶在激活过程中如何改变形状,识别了不同的活性位点类型和与c-Crk SH3域的相互作用. 这些发现揭示了c-Abl的亮点.

关键词:
亚比-1 亚比-1 是一个在AlphaFold2中,我们将使用AlphaFold2.适配器 适配器 适配器 适配器c-Abl交易激活方式c-Crkk 的意思是

更多相关视频

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays08:00

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays

Published on: December 4, 2016

8.0K
Advanced Self-Healing Asphalt Reinforced by Graphene Structures: An Atomistic Insight08:03

Advanced Self-Healing Asphalt Reinforced by Graphene Structures: An Atomistic Insight

Published on: May 31, 2022

5.6K

相关概念视频

Types of Non-structural Cracks in Concrete01:28

Types of Non-structural Cracks in Concrete

Non-structural cracks are primarily of three types: plastic, early-age thermal, and drying shrinkage cracks. Plastic cracks are further classified into plastic shrinkage cracks and plastic settlement cracks.
Plastic shrinkage cracks typically form within hours after the concrete is poured. The concrete's surface dries faster than the bottom, creating tensile stress that the still-plastic concrete cannot withstand, leading to diagonal or randomly patterned cracks on the concrete surface.
505
Accessory Structures of the Skin: Hair Growth and Types01:20

Accessory Structures of the Skin: Hair Growth and Types

Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
2.4K
Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
38.1K
Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
1.8K
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
26.4K
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
87.5K