与青年症状相关的个体特征报告和脑震荡后持续症状
S D Hicks1, B A Harding1, R Olympia2
1Department of Pediatrics, Penn State College of Medicine, Penn State University, Hershey, Pennsylvania, USA.
医疗和社会因素影响脑震荡症状报告和轻度创伤性脑损伤 (mTBI) 后的长期症状. 某些因素可能导致青少年在脑震荡后 (PSaC) 持续症状的过度检测.
科学领域:
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 在脑震荡后 (PSaC) 持续症状的标准化测量是具有挑战性的,因为有不和的方法.
- 预测轻度创伤性脑损伤 (mTBI) 后的长期症状需要了解影响因素.
- 社会人口统计学和医疗因素可能会影响mTBI后的症状负担和演变.
研究的目的:
- 确定与年轻人症状负担相关的医疗和社会人口学特征.
- 评估这些因素是如何影响症状演变的,以及在mTBI后的PSaC分类.
- 评估PSaC单项选器的实用性和潜在的错误分类风险.
主要方法:
- 1947年脑震荡后症状尺度分析报告来自1117名年轻人 (11-21岁).
- 包括mTBI,健康的非mTBI和非mTBI与潜在的医疗条件组.
- 多变量回归用于评估症状负担与医学/社会人口统计因素之间的关联,以及mTBI后的纵向影响.
主要成果:
- 基线症状负担与女性性别,神经精神病史,BMI和骨科损伤相关.
- 脑损伤后,年龄,性别和神经精神病史与症状负担相关;较小的家庭规模,体育参与和家长教育具有保护性.
- PSaC率 (mTBI后30天) 从14.7-18.9%不等,在定义上达成高度一致,但在患有医疗条件的非mTBI年轻人中,错误分类很高 (37.2-50.6%),特别是使用单项查仪.
结论:
- 医疗和社会人口统计学因素显著影响脑震荡症状报告和年轻人的演变.
- 这些因素影响了PSaC的分类,突出了对细微评估的需要.
- 虽然PSaC的单项查可能有所用,但它有可能在特定的年轻人群中过度检测.
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