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基底细胞和状细胞癌的侧向化:英国的一项回顾性横截面研究

Catharina Tao¹, Emma Guenther¹, Animesh Patel²

¹School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, United Kingdom.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

|January 31, 2026

概括

基础细胞癌 (BCC) 和状细胞癌 (SCC) 在英国队列中显示出统计学上显著的右侧主导地位. 这些发现表明皮肤癌侧面性和驾驶侧面性之间存在潜在联系,突出显示了需要防晒的需要.

科学领域:

皮肤病学皮肤病学
流行病学流行病学
公共卫生公共卫生

背景情况:

基底细胞癌 (BCC) 和状细胞癌 (SCC) 是常见的皮肤癌.
以前的研究表明,皮肤癌分布中的潜在横向性模式.
了解这些模式可能会为有关阳光照射的公共卫生信息提供信息.

研究的目的:

调查英国患者队列中BCC和SCC分布的横向性 (右与左).
通过子组分析识别特定模式.
探索与环境因素的潜在关联,如驾驶侧面.

主要方法:

从阿登布鲁克医院 (2018-2019) 活检确认的BCC和SCC病例的回顾性审查.
包括面部/头皮上的病变,不包括中线或不明确的位置.
使用奇平方或费舍尔精确测试来评估分布差异的统计分析.

主要成果:

观察到右侧BCC的统计学上显著占主导地位 (52%右侧,48%左侧;p=0.01).
还发现右侧SCC的统计学上显著占主导地位 (54%右侧,46%左侧;p=0.032).
在BCC和SCC中,以及在几个子组中,发现了右侧患病率.

结论:

该研究发现英国队列中BCC和SCC的右侧侧面显著.
这些发现与新兴的文献相一致,表明皮肤癌侧向性和驾驶时最容易暴露的身体侧面之间存在联系.
建议使用更大的数据集和调整的混因素进行进一步的研究,以加强这些结论,并为太阳安全活动提供信息,特别是针对驾驶员.

关键词:

基底细胞癌瘤是一种基本细胞癌.皮肤新生体的形成.状细胞癌瘤是一种状细胞癌.

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