瑞典1型糖尿病妇女的孕产妇结局. 一个基于人口的队列研究
Alexandra Goldberg1, Eva Wiberg-Itzel2, Joanna Tingström2
1Department of Clinical Science, Intervention and Technology - CLINTEC, Sweden.
概括
患有1型糖尿病 (T1D) 的女性患有妊娠并发症的风险显着更高,包括先兆子和增加对剖腹产等干预措施的需求. 这突显了为T1D孕妇提供专业的孕前和产周护理的迫切需要.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 1型糖尿病 (T1D) 与妊娠并发症的风险增加有关,例如先兆子和干预,由于高血糖和血管病变.
- 瑞典现有的对T1D孕妇的护理被认为是不公平的,需要对结果进行当前评估.
研究的目的:
- 在瑞典,对患有T1D的妇女的孕产妇和产科结果进行当代的重新评估.
- 调查与没有T1D的女性相比,T1D的女性怀孕并发症和干预措施的特定风险.
主要方法:
- 一项基于人口的队列研究,利用瑞典医疗出生登记册的数据.
- 包括有单子分娩 (妊娠22周以上) 和计划在2010-2022年间进行阴道分娩的初始产妇妇女 (N=558,546).
- 进行了后勤回归分析,以计算 95% 置信区间 (CI) 的调整赔率比率 (aOR).
主要成果:
- 与没有T1D的女性相比,患有T1D的女性 (n=2749) 显著增加了孕前的几率 (aOR 5.57),分娩诱导 (aOR 6.62),剖腹产 (aOR 4.71) 和肩膀缩 (aOR 11.81) 与没有T1D的女性相比 (n=555,797).
- 在患有T1D的女性中,真空提取,延长分娩,胎儿痛苦和产后子宫内膜炎的风险也增加了.
- 这些发现表明,对各种不良的孕产妇和产科结果的风险要大得多.
结论:
- 患有T1D的女性面临着妊娠并发症和分娩干预的显着增加的风险.
- 这项研究强调了量身定制的预孕和围产期护理策略的关键重要性.
- 有针对性的干预措施对于改善T1D患者的孕产妇和产科结果至关重要.
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