季节性和养变化在发育的pyloric狭窄症:一个回顾性病例对照研究研究
Cesar Kattini1, Meagan E Wiebe2, Victoria Larocca1
1Children's Hospital of Eastern Ontario Research Institute, 401 Smyth Rd, Ottawa, ON, Canada K1H 5B2.
Journal of pediatric surgery
|January 31, 2026
概括
婴儿甲状腺狭窄症 (PS) 的发病率在温暖的月份更高,与养习惯有关. 配方奶粉养的婴儿增加了PS风险,这表明可以修改的预防因素.
科学领域:
- 儿科外科手术 儿科外科手术
- 婴儿健康 婴儿健康
- 流行病学 流行病学
背景情况:
- 脊柱狭窄症 (PS) 是婴儿常见的一种手术条件.
- 人们还不完全了解PS的病因,可能会对环境产生影响.
- 以前的研究表明,季节性模式和养方法可能起作用.
研究的目的:
- 调查胆囊狭窄症发展与季节性变化之间的关联.
- 为了检查婴儿养习惯和甲状腺狭窄症发病率之间的关系.
主要方法:
- 对296名患有甲状腺狭窄症的婴儿和296名匹配的对照组 (2012-2022) 的回顾性图表审查.
- 病例和对照对性别,年龄和入院季节进行了匹配.
- 鱼类回归分析被用来评估季节和养习惯对PS发展的影响.
主要成果:
- 在季节和胆道狭窄发病率之间发现了统计学意义上的关联 (p=0.007).
- 皮隆狭窄症的发病率在夏季是最高的 (比冬季高出1.80倍).
- 与母乳养的婴儿相比,配方奶粉养的婴儿患甲状腺狭窄症的风险明显高 (3.7倍);混合养的婴儿患甲状腺狭窄症的几率是1.7倍.
结论:
- 皮洛里克狭窄症的发病率表现出显著的季节性变化.
- 婴儿养习惯,特别是配方养,与增加胆囊狭窄风险有关.
- 这些发现表明,可能是可修改的风险因素,为发育胆道狭窄症.
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