在灵长类前-双网络中,达到和掌握的混合选择性组织
Alireza Fathian1, Sebastian J Lehmann2, Jonathan A Michaels3
1Neurobiology Laboratory, Deutsches Primatenzentrum GmbH, Göttingen, Germany; Department of Biology and Psychology, University of Göttingen, Göttingen, Germany.
Progress in neurobiology
|January 31, 2026
概括
灵长类动物大脑中的神经元 (前侧内和腹前运动区域) 显示出混合的选择性,使得达到和抓取动作的灵活控制成为可能. 这种神经组织支持在不同任务中稳定,适应性强的运动控制.
科学领域:
- 神经科学是一个神经科学.
- 原始发动机控制器的主要功能是:
- 传感器-运动器集成.
背景情况:
- 伸出手和抓住涉及复杂的摩托控制握手类型,手腕方向,空间位置和手的侧向.
- 前侧内 (AIP) 和面额腹前运动 (F5) 区域是这些行动的关键神经枢纽.
研究的目的:
- 在AIP和F5区域内调查到达和抓取参数的神经编码.
- 了解神经元如何同时代表多个运动参数.
- 探索这个神经表示的时间动态和稳定性.
主要方法:
- 来自灵长类大脑的电生理学记录.
- 在达到和掌握任务期间分析神经元活动.
- 对抓握类型,对象定向和空间位置的神经选择性的研究.
主要成果:
- 神经元表现出主要混合的选择性,在运动和运动前阶段具有稳定的时间组织.
- 混合选择性允许灵活解码电机参数.
- 与物体相关的因素 (定向,位置) 在抓地变化期间在AIP中更稳定,而抓地类型在F5.5中更稳定.
- 尽管有条件依赖的变化,神经选择性在不同任务条件中在很大程度上保持不变.
结论:
- 在AIP和F5中的神经集群显示稳定的时间和功能组织,尽管在单个神经元水平上持续混合的选择性.
- 这种组织使灵活的运动控制和读数能够达到和抓取.
- 在AIP和F5.5之间存在上下文依赖编码的功能层次结构.
更多相关视频
16:45Nonhuman Primate Lung Decellularization and Recellularization Using a Specialized Large-organ Bioreactor
Published on: December 15, 2013
10.3K
08:42Assessment of Social Cognition in Non-human Primates Using a Network of Computerized Automated Learning Device ALDM Test Systems
Published on: May 5, 2015
12.6K
相关概念视频
Protein Networks
4.5K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.5K
What is Natural Selection?
129.1K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
129.1K
Network Covalent Solids
16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K
Mixing Concrete
383
Concrete mixing ensures a homogenous blend where aggregates are well-coated with cement paste. Concrete mixing is typically done using two main types of mixers: batch and continuous. Batch mixers handle one batch at a time, thoroughly combining materials before discharging and receiving the next batch. In contrast, continuous mixers receive a steady flow of ingredients, mixing them consistently and discharging without interruption. Within batch mixers, tilting drum mixers mix with internal...
383
Mixing Time
483
The concept of mixing time is significant in producing a uniform concrete mix with the required strength. The mixing period starts once all components are in the mixer. Initially, the mixer is charged with 10% of the water, followed by the consistent addition of solids and then 80% of the water. The remaining water is added later, within the first quarter of the mixing period. The minimum mixing time varies according to the mixer's capacity; for example, mixers with up to 1 cubic yard...
483
Ready Mixed Concrete
368
Ready-mixed concrete, also known as pre-mixed concrete, is prepared in a centralized plant and then transported in trucks to construction sites where it is ready for placement. This type of concrete is categorized into central-mixed, truck-mixed (or transit-mixed), and shrink-mixed. Central-mixed concrete is entirely prepared at a plant and moved to the site in agitator trucks that rotate at a speed of 2 to 6 rpm. Truck-mixed concrete, on the other hand, has the ingredients batched at the plant...
368
