在儿科胰腺炎中使用口服养:一项随机对照研究
Yan Han1, Hong Zhao1, Linchen Fu1
1Zhejiang University School of Medicine, National Clinical Research Center for Child Health, The Children's Hospital, Department of Gastroenterology, Hangzhou, China.
Jornal de pediatria
|January 31, 2026
概括
早期口服养对儿科急性胰腺炎 (AP) 有效,与鼻胃 (NG) 养相比,疼痛持续时间和体重变化相似. 口服养可能会减少轻度至中度AP儿童的并发症.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 营养疗法是一种营养疗法.
- 急性胰腺炎研究研究
背景情况:
- 早期的营养干预对于患有急性胰腺炎 (AP) 的儿童至关重要.
- 将口服养与鼻胃 (NG) 养进行比较对于优化儿科患者的AP管理至关重要.
研究的目的:
- 为了比较口服养与NG养在轻度至中度严重AP的儿童的疗效和安全性.
- 评估结果,包括疼痛持续时间,营养耐受性和体重变化.
主要方法:
- 一项前性随机对照试验,涉及48名儿科患者,患有轻度至中度AP.
- 参与者被随机分配到口服养或NG养组.
- 评估的主要结局是与AP相关的疼痛持续时间,耐受率和体重变化.
主要成果:
- 在口服和NG养组之间,没有观察到疼痛持续时间 (两组的中位数为3天) 或耐受率的显著差异.
- 在排放点和随访点 (排放后1周和5周) 的组之间,体重变化是可比的.
- 与NG组相比,口服养组的并发症较少 (0),但这种差异在统计学上并不显著 (p=0.109).
结论:
- 口服养是一种安全有效的营养策略,适用于轻度至中度AP的儿童.
- 这种方法可能会减少对侵入性手术的需要,例如NG管安置.
- 口服养在疼痛和体重方面表现出与NG养相似的疗效,并趋于减少并发症.
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