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Updated: Feb 2, 2026

A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants
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对抗原的量化和功能性评估(-) 瘤细胞变体

Ivan Odak1, Xinping Xie1, Gvantsa Pantsulaia1

  • 1Division of Hematology and Medical Oncology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Methods in cell biology
|January 31, 2026
PubMed
概括

像CAR T细胞这样的癌症免疫疗法可以导致抗原阴性瘤逃逸. 这项研究提出了一种新的方法来量化和评估这些耐药细胞,有助于克服治疗障碍.

关键词:
Ag- Ag- 的意思是抗原逃逸的方法抗原阴性 抗原阴性双特异性抗体 双特异性抗体BsAbBsAb 这是一个很好的例子.瘤是一个瘤.

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