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Updated: Feb 2, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Published on: March 2, 2014

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向缺氧外体IGFBP2克服了CD47介导的免疫逃避在质母细胞瘤

Yanhua Qi1,2, Rongrong Zhao1,2, Xinglong Zhang1,2

  • 1Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, Shandong, P. R. China.

Cell death & disease
|January 31, 2026
PubMed
概括

缺氧驱动胰岛素样生长因子结合蛋白2 (IGFBP2) 和质母细胞瘤 (GBM) 中的CD47表达,促进免疫逃避. 阻断IGFBP2和CD47协同抑制GBM生长,提供了一个新的治疗策略.

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