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Updated: Feb 2, 2026

A Versatile Murine Model of Subcortical White Matter Stroke for the Study of Axonal Degeneration and White Matter Neurobiology
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A Versatile Murine Model of Subcortical White Matter Stroke for the Study of Axonal Degeneration and White Matter Neurobiology

Published on: March 17, 2016

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中间前额前-体白质微观结构与强迫症的危害回避有关:一项发现和跨诊断复制研究

João Paulo Lima Santos1, Amelia Versace2,3, Manan Arora2

  • 1Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. limasantosjp2@upmc.edu.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
|January 31, 2026
PubMed
概括

背中中前额叶皮层 (PFC) - 丘脑通路中较高的分数异质性 (FA) 与精神疾病中伤害避免率的增加有关. 这一发现确定了一个跨诊断的神经点,用于开发针对强迫症等疾病的新疗法.

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相关概念视频

Classifying Matter by State02:49

Classifying Matter by State

Chemistry is the study of matter and the changes it undergoes. Matter is anything that has mass and occupies space. Matter is all around us; the air, water, soil, mountains, even our bodies are all examples of matter. Matter is divided into three states — solid, liquid, and gas — that are commonly found on earth. The fourth state of matter, plasma, occurs naturally in the interiors of stars. 
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Avoidance-avoidance conflict refers to a psychological situation where a person must choose between two or more unpleasant alternatives. These conflicts are particularly stressful because neither option is desirable. This dilemma is often expressed in sayings like "caught between a rock and a hard place" or "between the devil and the deep blue sea." For instance, individuals who fear dental procedures may find themselves torn between enduring a painful toothache or facing the...
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Classifying Matter by Composition

Matter: Pure Substances and Mixtures
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures. 
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Before a cell can divide, it must accurately replicate all of its chromosomes, including the DNA and its associated histone and non-histone proteins.  This process begins at numerous origins of replication during the S phase of the cell cycle in each of a cell’s chromosomes simultaneously. Certain nucleotides can act as origins of replication, but these sequences are not well defined - especially in complex, multi-cellular, eukaryotic species. The length of DNA that spans an origin...
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The characteristics that enable us to distinguish one substance from another are called properties.
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DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
Replication in Prokaryotes
DNA replication...
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