在患有伴随性PTSD和MDD的美国军人中,治疗结果的性别差异
Lisa H Glassman1,2, Nicholas P Otis3,4, Alexander C Kline3,4
1Psychological Health & Readiness Department, Naval Health Research Center, 140 Sylvester Road, , San Diego, CA, 92106, USA. lisa.h.glassman.ctr@health.mil.
BMC psychology
|January 31, 2026
概括
性影响美国服务人员患有PTSD和MDD的治疗结果. 标准CPT显示女性比男性更能减少PTSD症状,而BA+CPT则在两性之间具有相似的结果.
科学领域:
- 精神病学是一个精神病学.
- 军人卫生保健 军人卫生保健
- 临床心理学 临床心理学
背景情况:
- 伴并发性创伤后应激障碍 (PTSD) 和严重抑郁障碍 (MDD) 在服务人员中很常见.
- 识别治疗反应中的基于性别的差异对于优化护理至关重要.
研究的目的:
- 在美国现役服役人员中调查伴随性PTSD和MDD治疗结果的性别差异.
- 将标准认知处理疗法 (CPT) 与行为激活增强CPT (BA+CPT) 进行比较.
主要方法:
- 一项随机对照试验涉及94名美国现役服役人员 (55%的女性,45%的男性) 患有PTSD和MDD.
- 在治疗前,治疗后和3个月的随访期间评估PTSD和MDD症状严重程度.
- 利用多层次的治疗意图模型来根据性别分析治疗结果.
主要成果:
- 治疗条件缓和了性别和PTSD症状之间的关系 (p=.020).
- 与BA+CPT相比,在治疗后和随访时,服务女性的标准CPT显著减少了PTSD症状,与BA+CPT相比.
- 没有观察到军人或任何性别的BA+CPT条件的显著性别差异.
结论:
- 性别可能会对PTSD和MDD的治疗结果产生不同的影响,特别是标准CPT.
- 研究结果表明,标准的CPT对女性可能比男性更有效,患有并发性PTSD和MDD.
- 结果可以为个性化治疗方法的共享决策提供信息.
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