探索植物治疗药物对抗自身炎症性疾病的潜力:一篇评论
Sambhav Tyagi1, Snigdha Bhardwaj1, Kandasamy Nagarajan1
1Department of Pharmaceutics, KIET School of Pharmacy, KIET Group of Institutions, Ghaziabad, Delhi, NCR, India.
Current drug research reviews
|February 1, 2026
概括
植物药物通过减少炎症和氧化应激减轻关节炎的治疗有希望,为NSAIDs提供了替代品. 进一步的研究支持它们对炎症状况的潜在临床应用.
科学领域:
- 药理学 药理学是指药理学的学科.
- 免疫学 免疫学 免疫学
- 自然产品 化学 化学
背景情况:
- 炎症性疾病,如骨关节炎 (OA) 和类风湿性关节炎 (RA) 显著损害生活质量.
- 传统治疗 (NSAIDs) 携带诸如心血管疾病等风险.
- 草药为关节炎管理提供了潜在的治疗途径.
研究的目的:
- 审查关于草药在治疗关节炎和炎症方面的科学证据.
- 要突出具有抗炎和抗关节炎特性的植物性化合物.
主要方法:
- 来自PubMed和谷歌学者的2025年之前的研究的系统文献综述.
- 包括实验动物模型 (例如,原诱导的关节炎).
- 分析了182篇相关的研究文章.
主要成果:
- 草药配方有效地降低了炎症性细胞因子 (TNF-α,IL-1,IL-10,IL-18).
- 这些药物尽量减少氧化应激和关节炎症.
- 像黄素,Terminalia chebula和Moringa oleifera这样的化合物显示出治疗潜力.
结论:
- 药用植物具有科学支持的抗炎和抗关节炎活性.
- 草药证明了关节炎治疗的巨大潜力,尽管存在监管方面的挑战.
- 它们在控制炎症和氧化损伤方面的作用可能会增加未来的临床接受度.
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