儿科术后阿片类药物管理的医院单位变化与新生儿阿片类药物暴露增加有关
Kali Bravo1, Julie C McKee1, Russell Wells1
1Department of Surgery, Oregon Health & Science University, Portland, Oregon.
The Journal of surgical research
|February 1, 2026
概括
新生儿重症监护室 (NICU) 的患者在手术后使用的阿片类药物明显多于儿科病房的患者. 这凸显了需要改善NICU的阿片类药物管理,以减少婴儿手术后的阿片类药物暴露.
科学领域:
- 儿科手术 儿科手术
- 新生儿护理 新生儿护理
- 药理学 药理学是指药理学的学科.
背景情况:
- 在儿科外科护理中,阿片类药物管理至关重要.
- 在接受常见手术的婴儿中,阿片类药物的使用程度尚不清楚.
- 医院单位间阿片类药物管理的变化需要调查.
研究的目的:
- 为了比较腹腔镜胃口管放置后婴儿的阿片类药物管理模式.
- 评估新生儿重症监护室 (NICU) 和儿科病房患者之间阿片类药物使用的差异.
- 为了评估手术内和手术后的阿片类药物暴露.
主要方法:
- 进行腹腔镜胃口管安置 (2021-2023) 的患者的回顾性审查.
- 包括来自单个儿童医院的儿科和新生儿患者.
- 在手术期间和手术后48小时内,追踪每公斤 (MME/kg) 毫克相当的吗啡中阿片类药物暴露的情况.
主要成果:
- 总共分析了158名病房和51名NICU患者.
- 术内阿片类药物使用 (MME/kg) 在新生病重症监护室和病房患者之间没有显著差异.
- 与病房患者相比,NICU患者的术后阿片类药物使用,管理和暴露时间显著更高,即使在12个月以下的婴儿中也是如此.
结论:
- 与儿科病房患者相比,NICU患者在相同的手术后出现明显更高的术后阿片类药物使用.
- 需要进一步的研究来确定这种差异的原因.
- 优化阿片类药物管理和减少单位间的护理差异至关重要.
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