CFTR调节器在阿斯伯吉勒斯菌感染中部分恢复了上皮干扰组,以改善临床结果

Sarah L Laverty1, Imogen Felton2, Michelle Casey3

  • 1Imperial Fungal Science Network, Department of Infectious Disease, Imperial College London, UK; Immunology of Infection, Department of Infectious Disease, Imperial College London, UK.

EBioMedicine
|February 1, 2026
PubMed
概括

囊性纤维化跨膜导电调节器 (CFTR) 调节器通过恢复I/III型干扰素反应来改善阿斯伯吉路斯肺部疾病的结果. 外源的IFNλ1增强了中性粒细胞的抗真菌活性,这表明了一种新的治疗方法.

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