对Ibuzatrelvir对SARS-CoV-2循环变种和体外耐药性突变的活性进行分析

Irina Yurgelonis1, Devendra K Rai2, Zhenghui Li3

  • 1Anti-Infectives, Pfizer Research and Development, Pfizer Inc, Pearl River, NY 10965, USA.

Antiviral research
|February 1, 2026
PubMed
概括

一种新型的SARS-CoV-2 Mpro抑制剂Ibuzatrelvir显示出对主要变异的持续抗病毒疗效. 抗性突变很少见,支持其持续的临床评估来治疗COVID-19.

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