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Updated: Feb 3, 2026

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向 Mycobacterium 结核病 GAPDH 通过调节酶活性,氧化还原动力学和铁获取来引起强烈的杀菌反应

Zahid Gani1, Mohammad Naiyaz Ahmad2, Anurag Sindhu1

  • 1Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Phase X, Sector 67, SAS Nagar-160067, Punjab, India.

Free radical biology & medicine
|February 1, 2026
PubMed
概括

结核菌Mycobacterium Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) 作为氧化还原传感器,并通过像维生素C这样的化合物抑制其功能,增强了抗结核活性. 针对GAPDH提供了一个新的药物发现策略.

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