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作为抗结核病剂的5-英多利-皮拉尔设计的综合方法

K Mohammed Zabiulla1, Prabodh Ranjan2, Archakam Ranganatham3

  • 1Department of Chemistry, Government Science College, Bangalore 560001, Karnataka, India; Department of Chemistry, Bangalore University, Jnanabharathi Campus, Bengaluru 560056, Karnataka, India.

Bioorganic & medicinal chemistry letters
|February 1, 2026
PubMed
概括

结合英多尔和皮拉支架的新型混合分子对抗耐药菌株表现出强大的抗结核活性. 结构引导设计和分子对接揭示了下一代结核病治疗的有希望的化合物.

关键词:
抗结核病的药物可以治疗结核病.停靠对接 停靠对接印度尔 - 皮拉佐尔 (Indole-pyrazole) 是一种一种在hAAA中.结核病菌菌菌的结核病菌的结核病菌.

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