由于恶性淋巴瘤而导致的急性下肢动脉封闭:一个病例报告
Hana Isokawa1, Hiroshi Abe1, Dai Ozaki1
1Department of Cardiology, Juntendo University Urayasu Hospital, Japan.
Internal medicine (Tokyo, Japan)
|February 1, 2026
概括
纤维素相关的扩散性大B细胞淋巴瘤 (FA-DLBCL) 可以通过形成非典型的血栓引起急性四肢缺血症. 栓塞的病理评估对于诊断罕见的原因,如FA-DLBCL至关重要.
科学领域:
- 血管外科 血管外科
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 急性四肢缺血是一种血管紧急情况,通常是由动脉栓塞或血栓形成引起的.
- 壁面血栓,特别是与大动脉支架移植相关的,可以是栓塞的来源.
- 纤维素相关的扩散性大B细胞淋巴瘤 (FA-DLBCL) 是一种罕见的外节淋巴瘤,可以异常呈现.
研究的目的:
- 报告FA-DLBCL的次要急性四肢缺血病例,作为栓塞源.
- 强调在无法解释的急性四肢缺血病例中对血栓的病理检查的重要性.
- 提高对FA-DLBCL作为栓事件的潜在原因的认识.
主要方法:
- 一个72岁的男性患有急性左下肢缺血病的病例报告.
- 通过血栓切除术诊断急性动脉封闭.
- 血栓的病理分析显示了FA-DLBCL.
- 对成像 (PET-CT) 和尸检结果的审查.
主要成果:
- 血栓切除病理学在血栓内发现了FA-DLBCL.
- 最初没有检测到原发性淋巴瘤病变.
- 尸体解剖证实FA-DLBCL在一个壁状血栓中,距离大动脉支架移植.
- 这名患者在治疗下喉癌的放射治疗期间患上了肺炎,随后死亡.
结论:
- 在治疗急性四肢缺血症方面,非典型血栓的病理评估至关重要.
- 在分化诊断源自壁血栓的栓塞事件时,应考虑FA-DLBCL.
- 这一案例强调了FA-DLBCL的各种表现,以及全面的病理评估的重要性.
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