比较新的和传统的健康评估问卷评分方法:一种以患者为中心的干预网络对象研究
Yining Lu1, Daphna Harel2, Klint Kanopka3
1Y. Lu, MSc, Department of Applied Statistics, Social Science, and Humanities, New York University, New York, USA.
The Journal of rheumatology
|February 1, 2026
概括
对系统性硬化症 (SSc) 的健康评估问卷 (HAQ) 评分方法进行比较,发现HAQ残疾指数 (HAQ-DI) 由于其易于使用和可用的数据,是最实用的和首选的方法.
科学领域:
- 类风湿病学 类风湿病学
- 医学评估 医学评估
- 患者报告的结果
背景情况:
- 系统性硬化症 (SSc) 或硬皮症是一种慢性自身免疫性疾病,其特征是纤维化和血管异常.
- 准确测量功能障碍对于评估SSc患者的疾病影响和治疗疗效至关重要.
- 健康评估问卷 (HAQ) 是一个广泛使用的工具,但存在各种各样的评分方法,需要进行比较.
研究的目的:
- 在患有全身性硬化症 (SSc) 的人群中,对健康评估问卷 (HAQ) 进行五种不同的评分方法进行比较.
- 评估这些HAQ评分方法与物理功能,疼痛干扰和手部功能的外部测量相对应的趋同有效性.
主要方法:
- 脊髓灰质炎患者中心干预网络队列的参与者完成了20项HAQ.
- 通过五种方法计算得分:HAQ残疾指数 (HAQ-DI),替代残疾指数 (HAQ-ADI),修改HAQ (MHAQ),简单的总和得分和项目响应树 (IRTree) 模型.
- 使用Pearson与身体功能的相关性,疼痛干扰和手部功能的措施来评估收的有效性.
主要成果:
- 基于IRTree的得分与其他HAQ评分方法有很高的相关性 (r=0.90-0.95),与外部指标有中到强的相关性 (r=0.68-0.80).
- 基于IRTree和HAQ-DI与外部措施的相关性之间没有发现显著差异.
- 基于IRTree的得分优于HAQ-ADI,MHAQ和身体功能和疼痛干扰的总得分,但在手部功能方面表现更差.
结论:
- 项目响应树 (IRTree) 方法提供了一种新的HAQ数据评分方法,包括项目信息和援助使用情况.
- 尽管基于IRTree的评分是一种新的方法,但与标准HAQ-DI相比,基于IRTree的评分与外部措施没有表现出更好的关联.
- 由于其简单性,易于实施和广泛的支持性比较数据,HAQ残疾指数 (HAQ-DI) 仍然是首选的评分方法.
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